Pass the PTCB CPhT PTCE Questions and answers with CertsForce

Comprehensive and Detailed Step-by-Step Explanation:

The FDA Orange BookprovidesTherapeutic Equivalence (TE) codesto indicate whether a generic drug isequivalentto a brand-name drug.

????Explanation of Answer Choices:✅B. The Orange Book→Correct.Liststherapeutic equivalence (TE) codesfor FDA-approved generics.❌A. Remington→ Incorrect.Pharmacy reference book, not used for TE codes.❌C. SDSs→ Incorrect.Used for chemical safety, not drug equivalence.❌D. Package insert→ Incorrect.Does not contain TE codes.

????Reference:

FDA Orange Book

PTCB Exam: Therapeutic Equivalence

Comprehensive and Detailed Step-by-Step Explanation:

Glipizide (Glucotrol)is asulfonylurea, a class oforal hypoglycemic agentsused intype 2 diabetes. It works by stimulatinginsulin releasefrom the pancreas, which can causelow blood sugar (hypoglycemia)if insulin levels become too high.

Symptoms of Hypoglycemia:

Shakiness, sweating, dizziness

Confusion, irritability, rapid heartbeat

Severe cases: Seizures, unconsciousness

????Explanation of Answer Choices:✅C. Glipizide→Correct.Causeshypoglycemiaas it increases insulin secretion.❌A. Haloperidol→ Incorrect.Antipsychotic (Haldol), not related to blood sugar regulation.❌B. Gemfibrozil→ Incorrect.Lipid-lowering agent (fibrate), does not causehypoglycemia.❌D. Hydrochlorothiazide→ Incorrect.A diuretic that may cause hyperglycemia (increased blood sugar), not hypoglycemia.

????Reference:

American Diabetes Association (ADA) Guidelines on Hypoglycemia

USP Drug Classification Database

PTCB Exam: Diabetes Medications & Side Effects

Arexvyis anRSV (respiratory syncytial virus) vaccinefor adults60+ years.

Oncereconstituted, itmust be used within 4 hoursto ensurestability and potency.

After4 hours, bacterial growth andloss of vaccine efficacymake it unsafe for administration.

Why Other Options Are Incorrect:

A. 30 minutes?❌Too short—vaccines are stable for a longer duration.

C. 24 hours?❌Too long—Arexvy degrades faster.

D. 1 week?❌No vaccine remains effective for 7 days after reconstitution.

????Reference:CDC Vaccine Storage & Handling Guidelines,Arexvy Manufacturer Labeling (GSK).

To determine the required volume of U-100 insulin to administer a20-unitdose ofNPH insulin, we use the concentration definition:

U-100 insulinmeans100 units per 1 ml

We need20 units

Using the formula:

Volume (ml)=Dose (units)Concentration (units/ml)\text{Volume (ml)} = \frac{\text{Dose (units)}}{\text{Concentration (units/ml)}}Volume (ml)=Concentration (units/ml)Dose (units)​Volume=20 units100 units/ml=0.2 ml\text{Volume} = \frac{20 \text{ units}}{100 \text{ units/ml}} = 0.2 \text{ ml}Volume=100 units/ml20 units​=0.2 ml

Thus, the correct answer is0.2 ml.

A. 0.02 ml→ Incorrect; this would correspond to only 2 units.

B. 1 ml→ Incorrect; this would correspond to 100 units, far exceeding the prescribed dose.

D. 2 ml→ Incorrect; this would correspond to 200 units, which is incorrect.

Other Answer Choices Explained:References:

PTCB PTCE Exam Content Outline (Pharmaceutical Calculations)

USP <797> Pharmaceutical Compounding—Sterile Preparations

American Pharmacists Association (APhA) Pharmacy Technician Certification Review

Dilution formula:C₁V₁ = C₂V₂

C₁ = 20%, V₁ = 100 mL, C₂ = 2%

(20)(100) = (2)(V₂) → V₂ = 1000 mL(final volume after dilution).

Convert to oz:1000 mL ÷ 59 mL (2 oz) = 16 bottles.

????Reference:PTCE Pharmacy Dilution Calculations, USP <795> Guidelines.

????Reference:USP <797> Sterile Compounding Guidelines.

ISMP’s “Do Not Use” / error-prone abbreviations and dose designations emphasize avoiding trailing zeros (e.g., “120.0 mcg”), because the decimal point can be overlooked, potentially causing a tenfold error (e.g., read as 1200 mcg). ISMP also recommends using a leading zero before a decimal (e.g., 0.2 mg) to prevent misreads; thus 0.2 mg (A) and 1.4 mg (D) adhere to that guidance. 300 mcg (B) uses an acceptable unit (“mcg” rather than “µg”). Therefore, “120.0 mcg” (C) is the most error-prone due to the trailing zero.

References (Pharmacy Technician documents / Study Guides):

• ISMP Error-Prone Abbreviations, Symbols, and Dose Designations list: avoid trailing zeros; always use a leading zero before a decimal.

• PTCB/ExCPT medication safety sections covering safe dose expressions and ISMP recommendations.

• NCC MERP/ISMP educational materials on decimal point misinterpretation and tenfold dosing errors.

TheU.S. Food and Drug Administration (FDA)requires aMedication Guide (MedGuide)to be provided when dispensing certain medications that have significant safety concerns.Zyprexa (Olanzapine), anatypical antipsychotic, requires aMedication Guidedue to serious risks such as:

Increased mortality in elderly patients with dementia-related psychosis

Metabolic side effects(e.g., weight gain, hyperglycemia, and dyslipidemia)

Neuroleptic malignant syndrome (NMS)

A. Zafirlukast→ Incorrect; while used forasthma(leukotriene receptor antagonist), it doesnot require a Medication Guide.

B. Zestril (Lisinopril)→ Incorrect; anACE inhibitorfor hypertension, it doesnot require a Medication Guide.

C. Zinc→ Incorrect; adietary supplementthat does not require a Medication Guide.

Other Answer Choices Explained:References:

FDA Medication Guide Requirements for Olanzapine (Zyprexa)

PTCB PTCE Exam Content Outline (Medication Safety & Patient Counseling)

Comprehensive and Detailed Step-by-Step Explanation:

Cyclophosphamideis ahazardous drugclassified byNIOSH (National Institute for Occupational Safety and Health).USP Chapter 800mandates thatall surfaces exposed to hazardous drugs (HDs), including counting trays, must be decontaminated after each useto prevent cross-contamination.

????Explanation of Answer Choices:✅C. Decontaminated after each use→Correct.Hazardous drug residues must be removed after each use to prevent contamination.❌A. Activated before each use→ Incorrect. There is no"activation"process for hazardous drug counting trays.❌B. Disposed of after each use→ Incorrect.Counting trays are reusable but must be properly cleaned.❌D. Sterilized before each use→ Incorrect.Sterilization applies to sterile compounding, not hazardous drug handling.

????Reference:

USP <800>: Handling Hazardous Drugs in Healthcare Settings

NIOSH List of Hazardous Drugs (Cyclophosphamide)

Cefdinir is a cephalosporin (β-lactam) antibiotic. Patients with a penicillin allergy can have cross-reactivity with cephalosporins due to similar β-lactam structures, although the risk is lower with later generations like cefdinir. Because of this known potential cross-sensitivity, it is standard practice to assess for penicillin allergy when dispensing cephalosporins. Option A is incorrect because penicillin allergy is not an absolute, specific contraindication to cefdinir in all cases; risks must be assessed. Option B is incorrect (fluoroquinolones are unrelated class). Option D is overly general and not a standard rationale.

References (Pharmacy Technician documents/Study Guides):

• PTCB/ExCPT study materials on antibiotic classes and allergy cross-reactivity (β-lactams: penicillins and cephalosporins).

• ISMP medication safety guidance on allergy screening and β-lactam cross-sensitivity.

• Community pharmacy counseling references on assessing penicillin allergies before dispensing cephalosporins.