Fungal infections in immunocompromised patients (HIV/AIDS, chemotherapy patients, etc.)
Fluconazole works byinhibiting fungal ergosterol synthesis, which is essential for fungal cell membrane integrity.
A. Bacterial infections❌→Incorrect
Fluconazole does NOT treat bacterial infections; antibiotics are required instead.
B. Gastroesophageal reflux disease (GERD)❌→Incorrect
Proton pump inhibitors (PPIs) or H2 blockers(e.g., omeprazole, ranitidine) are used for GERD.
C. Altitude sickness❌→Incorrect
Acetazolamide (Diamox) is used for altitude sickness, not fluconazole.
FDA Fluconazole Drug Label– Confirms antifungal indications.
Centers for Disease Control and Prevention (CDC) Guidelines– Lists fluconazole asa treatment for candidiasis and cryptococcal meningitis.
PTCB PTCE Exam Content Outline– Covers antifungal medications and their indications.
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