Pass the NABP FPGEC Certification FPGEE Questions and answers with CertsForce

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Viewing questions 121-130 out of questions
Questions # 121:

For the majority of drugs, which of the following equations correctly defines clearance?

Options:

A.

Cl = Elimination rate/Cp


B.

Cl = QxE


C.

Cl = .7VD/t1/2


D.

All are correct


Expert Solution
Questions # 122:

Side effect of actinomycin D is:

Options:

A.

Bronchospasm


B.

Hypotension


C.

GI toxicity


D.

Oral and GI ulcers


E.

Dysphonia


Expert Solution
Questions # 123:

Mechanism of action of doxorubicin is:

Options:

A.

Inhibits topoisomerase II


B.

alpha antagonist


C.

Inhibits peptidyl transferase


D.

beta antagonist


E.

Allosterically enhances GABAergic inhibition


Expert Solution
Questions # 124:

Which of the following Cytochrome P450 isozymes is responsible for the bulk of phase I metabolism?

Options:

A.

CYP1A2


B.

CYP2C9


C.

CYP2D6


D.

CYP3A4


E.

CYP51


Expert Solution
Questions # 125:

Which of the following are similarities between Cytochrome P450 and MAO?

Options:

A.

Both add oxygen from O2 to substrates and also form water


B.

Both carry out direct heteroatom oxidations


C.

Both carry out oxidative deaminations


D.

Both carry out N-dealkylations


E.

All of the above


Expert Solution
Questions # 126:

Which of the following is considered a class IA Sodium Channel blocker?

Options:

A.

Propafenone


B.

Disopyramide


C.

Aminodarone


D.

Quinidine


Expert Solution
Questions # 127:

Which of the following statements refers to etidronate?

Options:

A.

Binds to DNA, preferentially to GC pairs. Inhibits RNA, DNA, and protein synthesis.


B.

Human, pig, salmon, and eel calcitonins are available.


C.

Is used for both therapy and prophylaxis of influenza A.


D.

Bioavailability increases with administered dose.


E.

Only approved by FDA for hypertension treatment.


Expert Solution
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Viewing questions 121-130 out of questions