Acute severe aortic regurgitation causes rapid volume overload of the left ventricle during diastole, leading to a marked increase in left ventricular end-diastolic pressure (LVEDP). This elevated LVEDP results from the sudden return of blood into the ventricle and impaired compliance.
End-systolic pressure is not primarily affected. Early-diastolic pressure changes relate to aortic pressure but LVEDP is critical. Early-systolic pressure is not typically affected by AR.
This hemodynamic effect is discussed in the "Textbook of Clinical Echocardiography, 6e", Chapter on Aortic Regurgitation and Hemodynamics【20:375-380†Textbook of Clinical Echocardiography】.
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