The most common symptom of cholelithiasis (gallstones) is biliary colic, characterized by intermittent right upper quadrant or epigastric pain often triggered by fatty meals. Jaundice occurs in complications such as choledocholithiasis.

According to Rumack’s Diagnostic Ultrasound:

“Gallstones may cause biliary colic — episodic upper abdominal pain often related to food intake.”