Direct inguinal hernias protrude through Hesselbach's triangle, which lies medial to the inferior epigastric artery. In contrast, indirect inguinal hernias pass lateral to the inferior epigastric artery via the deep inguinal ring.

According to Moore’s Clinically Oriented Anatomy:

“Direct inguinal hernias occur medial to the inferior epigastric vessels, within Hesselbach's triangle.”