American Society of Microbiology ABMM ABMM Question # 57 Topic 1 Discussion

American Society of Microbiology ABMM ABMM Question # 57 Topic 1 Discussion

ABMM Exam Topic 1 Question 57 Discussion:
Question #: 57
Topic #: 1

During a primary infection with Epstein-Barr virus (EBV), the virus establishes latency in B lymphocytes. The transition from lytic to latent infection is tightly regulated by viral gene expression. Which of the following viral proteins is crucial for the establishment and maintenance of EBV latency and is a key target in EBV-associated lymphomas?


A.

Viral capsid antigen (VCA)


B.

Early antigen (EA)


C.

Epstein-Barr nuclear antigen 1 (EBNA1)


D.

Glycoprotein gp350


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