American Society of Microbiology ABMM ABMM Question # 56 Topic 1 Discussion

American Society of Microbiology ABMM ABMM Question # 56 Topic 1 Discussion

ABMM Exam Topic 1 Question 56 Discussion:
Question #: 56
Topic #: 1

A patient with a history of recurrent Clostridioides difficile infection (CDI) is being considered for fecal microbiota transplantation (FMT). Pre-FMT screening of the donor stool sample should include comprehensive testing to exclude potential transmission of enteric pathogens. Which of the following would be the MOST critical to rule out in the donor stool?


A.

Presence of non-toxigenic C. difficile strains.


B.

Detection of common antibiotic resistance genes not currently expressed.


C.

Evidence of asymptomatic carriage of multidrug-resistant organisms (MDROs) such as vancomycin-resistant enterococci (VRE) or carbapenem-resistant Enterobacterales (CRE).


D.

Quantification of the overall microbial diversity using 16S rRNA gene sequencing.


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