• Enbrel (etanercept) is a biologic that requires refrigeration at 2–8°C (36–46°F) prior to dispensing and during storage per manufacturer labeling.

• Testosterone injections (e.g., cypionate/enanthate) are typically stored at controlled room temperature.

• Lovenox (enoxaparin) prefilled syringes and heparin injections are also stored at controlled room temperature; refrigeration is not required.

Therefore, the injection that must be refrigerated is Enbrel.

References (Pharmacy Technician Documents/Study Guides):

• Storage and stability in manufacturer labeling for biologics and injectables; pharmacy technician references on refrigerated biologics (e.g., etanercept) vs. room-temperature injectables (testosterone, enoxaparin, heparin).