Penetration testing is the best method for assessing control effectiveness against technical vulnerabilities that could be exploited to compromise an information system, as it simulates areal-world attack scenario and evaluates the security posture of the system. Penetration testing is a type of security testing that involves performing authorized and ethical hacking activities on a system to identify and exploit its vulnerabilities and weaknesses. Penetration testing can help to measure and improve the effectiveness and efficiency of the controls implemented to protect the system from unauthorized access, modification, or damage.

The other options are not the best methods for assessing control effectiveness against technical vulnerabilities that could be exploited to compromise an information system. Vulnerability scanning is an automated process that uncovers potential vulnerabilities in systems and software, but it does not provide information on the impact and severity of the vulnerability or how they can be exploited using different exploitation techniques1. Systems log correlation analysis is a process of examining and analyzing the records of system activities and events, but it does not directly test the controls or simulate the attack scenarios. Monitoring of intrusion detection system (IDS) alerts is a process of tracking and auditing the system or network for any signs of malicious or anomalous activities, but it does not evaluate the control performance or identify the root causes of the vulnerabilities. References = Vulnerability Assessment Principles | Tenable®, A Complete Guide on Vulnerability Assessment Methodology, Karen Scarfone Scarfone Cybersecurity - NIST Computer Security Resource …