The best recommendation is to align the IT strategy with the business objectives. This will ensure that the IT projects and initiatives are consistent with the organization’s vision, mission, and goals. IT strategy should be derived from and support the business strategy, not the other way around. By aligning the IT strategy with the business objectives, the organization can achieve better value, performance, and alignment from its IT investments.

Reviewing priorities in the IT portfolio (option B) is not the best recommendation, as it does not address the root cause of the misalignment between the IT strategy and the IT portfolio. The IT portfolio should reflect the IT strategy, which in turn should reflect the business objectives. Simply changing the priorities in the IT portfolio without aligning the IT strategy with the business objectives may result in suboptimal or conflicting outcomes.

Changing the IT strategy to focus on operational excellence (option C) is also not the best recommendation, as it may not be aligned with the business objectives. The organization’s IT strategy should be based on its competitive advantage, market position, customer needs, and industry trends. If the organization’s business strategy is heavily focused on research and development, then changing the IT strategy to focus on operational excellence may not be appropriate or beneficial.

Aligning the IT portfolio with the IT strategy (option D) is also not the best recommendation, as it does not address the misalignment between the IT strategy and the business objectives. Aligning the IT portfolio with the IT strategy may improve the coherence and consistency of the IT projects, but it may not ensure that they are aligned with the organization’s vision, mission, and goals.

Therefore, option A is the correct answer.