Cohesity: Provides a backup and recovery solution with NFS, SMB, and S3 features.

Commvault: Integrates with StoreOnce Catalyst for deduplication of data.

Zerto: Provides disaster recovery for only VMs.

Enterprise data protection requires selecting the right software partner to align with specific infrastructure needs, whether protecting bare-metal servers, virtualized workloads, or modern unstructured data.

Cohesity: This solution is defined by its "multicloud data platform" approach. It is often used to consolidate secondary storage silos by providing a single platform that handles not only backup and recovery but also serves as a scale-out NAS. It natively provides NFS, SMB, and S3 features, allowing it to act as a target for unstructured data while simultaneously protecting applications and VMs.

Commvault: As a long-standing leader in enterprise backup, Commvault features deep, verified integration with HPE hardware. A key differentiator for HPE customers is how Commvault integrates with StoreOnce Catalyst. This integration allows Commvault to manage the movement of deduplicated data directly to StoreOnce appliances without needing to rehydrate the data, significantly reducing network traffic and storage costs across the enterprise.

Zerto: Unlike traditional backup products that rely on snapshots, Zerto utilizes continuous data protection (CDP) through the hypervisor layer. While it is a powerhouse for replication and orchestration, it is architecturally focused on virtualized environments. Within the context of this comparison, it is the solution that provides disaster recovery for only VMs, as its Virtual Replication Appliances (VRAs) are purpose-built to intercept I/O within VMware or Hyper-V environments.