To perform DLP scanning on Cisco ESA, two components must be configured:
Add a DLP policy to the DLP Policy Manager, which is a repository of predefined or custom DLP policies that specify what types of data to scan for and what actions to take if a match is found.
Enable a DLP policy on the Outgoing Mail Policy, which is a set of rules that determine how outgoing messages are processed by Cisco ESA, including whether to apply DLP scanning or not.
References: User Guide for AsyncOS 15.0 for Cisco Secure Email Gateway, page 9-2 and page 9-4.
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