High-sensitivity C-reactive protein (hs-CRP) is used as an aid in the diagnosis and treatment of cardiovascular disease (CVD). At low levels, it can detect those at risk for cardiac heart disease. At high levels in those with no history of heart disease, it indicates a high risk for acute myocardial infarction (AMI), stroke, or peripheral vascular disease. For patients with acute coronary syndrome (ACS) or stable coronary disease, hs-CRP is used to predict future coronary events.

Ranges of hs-CRP in prediction of risk for CVD are:

<1.0 mg/L Low CVD risk

1.0-3.0 mg/L Average risk for CVD

>3.0 mg/L High risk for future CVD

If results are >10.0 mg/L, the patient should be evaluated for an acute inflammatory condition.

Chemistry

A high-sensitivity C-reactive protein (hs-CRP) test result of 5 mg/L (normal = < 1 mg/L) may indicate which of the following?