Create an interface VPC endpoint for Amazon S3 in the subnet where the EC2 instance is located. Attach a resource policy to the S3 bucket to only allow the EC2 instance's IAM role for access.

Create a gateway VPC endpoint for Amazon S3 in the Availability Zone where the EC2 instance is located. Attach appropriate security groups to the endpoint. Attach a resource policy lo the S3 bucket to only allow the EC2 instance's IAM role for access.

Run the nslookup tool from inside the EC2 instance to obtain the private IP address of the S3 bucket's service API endpoint. Create a route in the VPC route table to provide the EC2 instance with access to the S3 bucket. Attach a resource policy to the S3 bucket to only allow the EC2 instance's IAM role for access.

Use the AWS provided, publicly available ip-ranges.json tile to obtain the private IP address of the S3 bucket's service API endpoint. Create a route in the VPC route table to provide the EC2 instance with access to the S3 bucket. Attach a resource policy to the S3 bucket to only allow the EC2 instance's IAM role for access.