This requirement combines asynchronous inference on large datasets with automated data quality monitoring and alerting. AWS documentation explicitly recommends Amazon SageMaker batch transform for large-scale, asynchronous inference workloads. Batch transform jobs process large datasets stored in Amazon S3 without requiring a persistent endpoint, making them cost-effective and scalable.

For data quality monitoring, Amazon SageMaker Model Monitor is the AWS-native solution. Model Monitor can be scheduled to analyze inference data, compare it against a baseline, and detect data quality issues such as missing values, schema changes, or statistical drift. When violations occur, Model Monitor emits metrics to Amazon CloudWatch, where alarms can trigger alerts.

Options A, B, and C lack ML-aware data quality monitoring capabilities. AWS Glue and Batch are not designed for model data quality analysis, and CloudTrail tracks API activity—not data quality.

AWS best practices clearly position Batch Transform + Model Monitor as the correct architecture for asynchronous inference with automated monitoring and alerting.

Therefore, Option D is the correct and AWS-verified solution.