The requirement is to quickly determine whether the target variable is predictable, with minimal development effort. Amazon SageMaker Autopilot is specifically designed for this purpose.

SageMaker Autopilot automatically handles data preprocessing, feature engineering, algorithm selection, model training, and evaluation. It generates multiple candidate models and provides detailed performance metrics, allowing teams to quickly assess predictability without writing custom code.

Option B requires significant manual development. Option C is incorrect because Amazon Macie is a data security and classification service, not an ML modeling service. Option D is unsuitable because Amazon Bedrock models are not intended for structured tabular prediction tasks.

Therefore, SageMaker Autopilot provides the fastest and least effort solution.