While patients with hypoplastic left heart syndrome (HLHS) typically have lower baseline oxygen saturations due to mixing of systemic and pulmonary blood flow,feverin this population is especially concerning due to theirimmunocompromised and pre-transplant status. Fever may signalinfection or sepsis, both of which can jeopardize transplant eligibility and lead to rapid decompensation.
“In patients awaiting heart transplantation, fever is a red flag for infection or systemic inflammatory response, both of which significantly increase mortality risk and complicate transplant candidacy. Prompt evaluation is required.”
(Referenced from CCRN Pediatric – Direct Care: Cardiovascular, Pre-Transplant Management)
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