The best way to address the performance issues and time-outs faced by the Store Manager team is to configure a dedicated virtual warehouse for them and make it multi-clustered. This will allow them to run their reports independently from other workloads and scale up or down the compute resources as needed. A dedicated virtual warehouse will also enable them to apply specific security and access policies for their data. A multi-clustered virtual warehouse will provide high availability and concurrency for their queries and avoid queuing or throttling.

Using a Business Intelligence tool for in-memory computation may improve performance, but it will not solve the underlying issue of insufficient compute resources in the shared virtual warehouse. It will also introduce additional costs and complexity for the data architecture.

Configuring the virtual warehouse to size 4-XL may increase the performance, but it will also increase the cost and may not be optimal for the workload. It will also not address the concurrency and availability issues that may arise from sharing the virtual warehouse with other workloads.

Advising the Store Manager team to defer report execution to off-business hours may reduce the load on the shared virtual warehouse, but it will also reduce the timeliness and usefulness of the reports for the business. It will also not guarantee that the performance issues and time-outs will not occur at other times.