To automate a workflow that requires data transfer between two Salesforce orgs and a distinct multi-user workflow within one of the orgs, the following tools are recommended:

MuleSoft Composer:

MuleSoft Composer allows for easy and quick integration between multiple systems, including different Salesforce orgs. It provides a no-code solution for connecting and syncing data across Salesforce instances.

Use MuleSoft Composer to create the integration flows that handle the data transfer between the two Salesforce orgs.

Flow Orchestration:

Salesforce Flow Orchestration is ideal for automating complex, multi-step business processes involving multiple users within a single org.

Use Flow Orchestration to design and automate the distinct multi-user workflow within one of the Salesforce orgs. It helps in coordinating user tasks, approvals, and other business processes seamlessly.

Combining these two tools leverages their strengths to handle both the integration and the complex workflow automation efficiently.