Comprehensive and Detailed Step-by-Step Explanation:
Adsorption occurs when a drug binds to a surface (e.g., IV tubing), reducing its potency.Some drugs, likeinsulin and nitroglycerin,canadhere to plastic tubing, reducing the active dose the patient receives.
????Explanation of Answer Choices:✅A. Lose potency→Correct.Adsorptionreduces drug strength.❌B. Become contaminated→ Incorrect.Adsorption does not introduce contaminants.❌C. Require refrigeration→ Incorrect.Refrigeration is unrelated to adsorption.❌D. Trigger anaphylaxis→ Incorrect.Adsorption does not cause allergic reactions.
????Reference:
USP <797>: Sterile Compounding
ISMP Guidelines on IV Drug Stability
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