Configure a dynamic address group for the addresses to be blocked with the tag "malicious." Add a Log Forwarding profile to the other policies, which adds the "malicious" tag to these addresses when logs are generated in the threat log. Under Device > User Identification > Trusted Source Address, add the condition "NOT malicious."

Configure a dynamic user group for the users to be blocked with the tag "malicious." Add a Log Forwarding profile to the other policies, which adds the "malicious" tag to these users when logs are generated in the threat log. Create policies to block traffic from this user group.

Configure the appropriate security profiles for Antivirus, Anti-Spyware, and Vulnerability Prevention, create signature policies for the relevant signatures and/or severities. Under the "Actions" tab in "Signature Policies," select "block-user."

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