Teach-back is an evidence-based communication strategy that confirms patient understanding by asking them to repeat instructions in their own words. It is effective for improving medication adherence because it identifies gaps in knowledge and reinforces comprehension (The Joint Commission, Communication Best Practices, 2024; Agency for Healthcare Research and Quality, Health Literacy, 2023). Evaluating barriers (B) and medication reconciliation (C) are important but do not directly verify patient understanding. Printed materials (D) support education but may be insufficient alone, especially with low health literacy populations. Teach-back fosters patient engagement and reduces readmissions.