Deterioration in a clinical outcome measure (e.g., infection rates) suggests an underlying issue in care delivery. The initial step should investigate contributing factors.

Option A (Analyze related process measure performance): This is the correct answer. The NAHQ CPHQ study guide states, “When outcomes deteriorate, analyzing related process measures (e.g., hand hygiene compliance for infection rates) identifies root causes” (Domain 4). This aligns with the Donabedian model, linking processes to outcomes.

Option B (Re-educate staff on appropriate clinical outcomes): Re-education assumes a knowledge gap, which is premature without identifying the cause of deterioration.

Option C (Review current best practices on areas of deterioration): Best practice review is a later step after understanding the specific issue.

Option D (Assess data entry errors in areas of deficiency): Data errors are a possible cause but not the first step, as process issues are more likely to drive clinical outcomes.

CPHQ Objective Reference: Domain 4: Performance and Process Improvement, Objective 4.5, “Analyze performance data to identify improvement opportunities,” emphasizes linking outcome deterioration to process measures. The NAHQ study guide advocates for process analysis as the initial step in outcome investigations.

Rationale: Analyzing process measures provides insight into why outcomes deteriorated, guiding targeted interventions, as per CPHQ improvement methodologies.