Quality improvement initiatives require prioritization to ensure resources are allocated effectively, given the constraints of time, staff, and funding.

Option A (Some improvements are not meaningful): While some improvements may have less impact, this is not the primary reason for prioritization. The focus is on resource allocation rather than dismissing improvements as meaningless.

Option B (Few processes require improvement): This is incorrect, as most organizations have multiple processes needing improvement. The challenge is choosing which to address first.

Option C (Many organizations lack the resources to improve all processes): This is the correct answer. NAHQ CPHQ study materials emphasize that organizations must prioritize quality improvement due to limited resources (e.g., staff, budget, time), focusing on high-impact, high-risk, or high-cost processes to maximize outcomes.

Option D (There are difficulties in accurately measuring improvement): Measurement challenges exist but are not the primary driver for prioritization. Prioritization is driven by resource constraints and strategic alignment.