To communicate asynchronously between two APIs deployed to a two-node on-prem cluster, the developer can use the VM Connector if the two APIs use the same domain. The VM Connector allows passing messages between different Mule applications within a single Mule runtime instance or across different instances using shared memory or persistent storage. If two APIs are deployed under the same domain, they can share resources such as VM queues and communicate asynchronously using VM Connector operations. References: https://docs.mulesoft.com/mule-runtime/4.3/vm-connector https://docs.mulesoft.com/mule-runtime/4.3/shared-resources