Zero-day malware is malware that exploits unknown and unprotected vulnerabilities. This novel malware is difficult to detect and defend against, making zero-day attacks a significant threat to enterprise cybersecurity1. The best way to detect zero-day malware on an end user’s workstation is to use file integrity monitoring, which is a technique that monitors and alerts on changes to files and directories that may indicate a malware infection or compromise2. By using fileintegrity monitoring, the end user can detect zero-day malware that may alter or damage the files or directories on their workstation, and take appropriate actions to remove or isolate the malware. File integrity monitoring can also help to prevent the spread of zero-day malware to other systems or networks, and to restore the integrity and availability of the affected files or directories. Antivirus program, database activity monitoring, and firewall log monitoring are not the best ways to detect zero-day malware on an end user’s workstation, as they are not as effective or reliable as file integrity monitoring. Antivirus program is a software that scans and removes known malware from a system or network3. Antivirus program can help to protect the end user’s workstation from common or known malware, but it may not be able to detect zero-day malware that does not have a signature or a pattern that matches the antivirus program’s database. Database activity monitoring is a technique that monitors and audits the activities and transactions on a database, such as queries, updates, or deletions4. Database activity monitoring can help to protect the end user’s database from unauthorized or malicious access or modification, but it may not be able to detect zero-day malware that does not target or affect the database. Firewall log monitoring is a technique that monitors and analyzes the logs generated by a firewall, which is a device or software that filters and controls the incoming and outgoing network traffic based on predefined rules. Firewall log monitoring can help to protect the enduser’s workstation from external or internal network attacks, but it may not be able to detect zero-day malwarethat bypasses or evades the firewall rules or that originates from the workstation itself. References = 1: What is Zero Day Malware? - Check Point Software2: File Integrity Monitoring - an overview | ScienceDirect Topics3: Antivirus Software - an overview | ScienceDirect Topics4: Database Activity Monitoring - an overview | ScienceDirect Topics : [Firewall Log Analysis - an overview | ScienceDirect Topics] : [Risk and Information Systems Control Study Manual, Chapter 5: Information Systems Control Design and Implementation, Section 5.1: Control Design, pp. 233-235.] : [Risk and Information Systems Control Study Manual, Chapter 5: Information Systems Control Design and Implementation, Section 5.2: Control Implementation, pp. 243-245.] : [Risk and Information Systems Control Study Manual, Chapter 5: Information Systems Control Design and Implementation, Section 5.3: Control Monitoring and Maintenance, pp. 251-253.] : [Zero-day attack detection: a systematic literature review | Artificial Intelligence Review] : [Zero-day Attacks Detection and Prevention Methods | Apriorit]