Hypoxic air systems continuously reduce the oxygen concentration in the protected area to below the level required for combustion (typically 15–16%), while still remaining safe for human occupancy (>14%). By lowering oxygen concentration, ignition and flame propagation are prevented.

This is different from halocarbon or inert-gas clean agents, which flood the room only upon detection of fire. Hypoxic systems are preventive, creating a permanent fire-retardant environment.

They do not remove heat (A), fuel (C), or use water (D). Their key mechanism is oxygen displacement.