Command-and-control (C2) beaconing involves compromised systems communicating with an attacker’s server at regular intervals, often using HTTPS to blend in with legitimate traffic. This is indicative of a potential compromise where malware communicates back to a command center. The persistent nature of the connections after hours and throughout the day suggests automated beaconing, which is a tell-tale sign of C2 activity. According to CompTIA CySA+, this type of activity should raise immediate suspicion and warrants further investigation and containment. While options B, C, D, and E might indicate other issues, they do not fit the pattern described as well as option A.