Cisco ISE uses probes to collect endpoint attributes that are used in profiling. Probes are software modules that run on the ISE Policy Service Nodes (PSNs) and gather information about the endpoints connected to the network. Probes can use various protocols and methods to collect endpoint attributes, such as RADIUS, DHCP, SNMP, HTTP, DNS, NetFlow, NMAP, Active Directory, and Cisco pxGrid. The collected attributes are then matched to predefined or custom conditions that define the endpoint profiles. Endpoint profiling enables ISE to identify and classify the endpoints and apply the appropriate policies based on their identity, role, and context12. References: 1: Cisco ISE 2.4 Endpoint Profiling - Cisco 2: How To Create an Endpoint Profile - Cisco Community