Contrast agents used in echocardiography can rarely cause anaphylactoid reactions, which are non-IgE-mediated hypersensitivity reactions that can mimic anaphylaxis. Therefore, sonographers must be prepared to manage such reactions.
Contrary to option B, reactions can be severe though rare. Even patients without prior allergies can react. It is incorrect to say the exam poses no risk; proper precautions and monitoring are essential.
These precautions are emphasized in ASE contrast echocardiography guidelines and safety protocols【12:ASE Contrast Echocardiography Guidelines†p.190-195】【16:Textbook of Clinical Echocardiography, 6e†p.575-580】.
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