American Society of Microbiology ABMM ABMM Question # 76 Topic 3 Discussion
ABMM Exam Topic 3 Question 76 Discussion:
Question #: 76
Topic #: 3
Acyclovir is a commonly used antiviral agent effective against Herpes Simplex Virus (HSV) and Varicella-Zoster Virus (VZV). Its selective toxicity relies on which initial step for activation within infected cells?
A.
Phosphorylation by host cell mitochondrial kinases
B.
Monophosphorylation primarily by viral thymidine kinase
C.
Direct inhibition of viral RNA polymerase activity
D.
Blocking viral entry through competitive inhibition of cellular receptors
Chosen Answer:
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