Option A and B are the correct answers because they meet the requirements most cost-effectively. Using an AWS Lambda function and the Athena Boto3 client start_query_execution API call to invoke the Athena queries programmatically is a simple and scalable way to orchestrate the queries. Creating an AWS Step Functions workflow and adding two states to check the query status and invoke the next query is a reliable and efficient way to handle the long-running queries.

Option C is incorrect because using an AWS Glue Python shell job to invoke the Athena queries programmatically is more expensive than using a Lambda function, as it requires provisioning and running a Glue job for each query.

Option D is incorrect because using an AWS Glue Python shell script to run a sleep timer that checks every 5 minutes to determine whether the current Athena query has finished running successfully is not a cost-effective or reliable way to orchestrate the queries, as it wastes resources and time.

Option E is incorrect because using Amazon Managed Workflows for Apache Airflow (Amazon MWAA) to orchestrate the Athena queries in AWS Batch is an overkill solution that introduces unnecessary complexity and cost, as it requires setting up and managing an Airflow environment and an AWS Batch compute environment.

AWS Certified Data Engineer - Associate DEA-C01 Complete Study Guide, Chapter 5: Data Orchestration, Section 5.2: AWS Lambda, Section 5.3: AWS Step Functions, Pages 125-135

Building Batch Data Analytics Solutions on AWS, Module 5: Data Orchestration, Lesson 5.1: AWS Lambda, Lesson 5.2: AWS Step Functions, Pages 1-15

AWS Documentation Overview, AWS Lambda Developer Guide, Working with AWS Lambda Functions, Configuring Function Triggers, Using AWS Lambda with Amazon Athena, Pages 1-4

AWS Documentation Overview, AWS Step Functions Developer Guide, Getting Started, Tutorial: Create a Hello World Workflow, Pages 1-8