Understanding the environmental impacts of various refrigerants is crucial for energy managers. Let's analyze each statement:​en.wikipedia.org

A.R-407C is a blended Hydro Fluoro Carbon or near Azeotropic mixture, and can be used as a replacement for R-22 in commercial applications:This statement is correct. R-407C is a blend of HFCs designed to replace R-22 in air conditioning systems.

B.R-11 and R-12 are Chloro Fluoro Carbons with significant ozone depleting potential:This is correct. R-11 and R-12 are CFCs known for their high ozone depletion potential.

C.R-1234yf is a Hydro Fluoro Olefin with zero ozone depleting potential, and little global warming potential:Correct. R-1234yf is an HFO with negligible ozone depletion and low global warming potential.

D.R-22 is a Hydro Chloro Carbon with significant ozone depleting potential and significant global warming impact:This statement is incorrect.R-22 is a Hydrochlorofluorocarbon (HCFC), not a Hydro Chloro Carbon.While it does have ozone-depleting potential, its global warming potential is considered moderate, not significant.

E.R-32 and R-134a are Hydro Fluoro Carbons with zero ozone depleting potential, and significant global warming impact:This is correct. Both R-32 and R-134a are HFCs with no ozone depletion potential but have considerable global warming potential.

Conclusion:

The incorrect statement is D. R-22 is a Hydro Chloro Carbon with significant ozone depleting potential and significant global warming impact. Therefore, the correct answer is D.