To connect the workload network segment to their on-premises data center and multiple company Amazon VPCs running in US-East-2, the customer can use VMware Transit Connect. VMware Transit Connect is a service that provides secure connectivity between AWS and on-premises data centers or other clouds. It allows customers to connect and extend their networks to the AWS cloud with minimal effort and cost.

VMware Transit Connect provides high-speed, resilient connectivity and is integrated with the AWS Transit Gateway. With VMware Transit Connect, customers can connect their software-defined data center (SDDC) network, Amazon Virtual Private Clouds (VPCs), and on-premises data centers. This allows them to have a seamless networking connectivity between their VMware Cloud on AWS SDDC and their native AWS environment. So, for the given scenario where the customer wants to connect to both their on-premises data center and multiple VPCs in the same AWS region, VMware Transit Connect would be the most appropriate choice.

https://blogs.vmware.com/networkvirtualization/2020/09/vmware-transit-connect-simplifying-networking-for-vmc.html/