If a blood sample is drawndistal (downstream)from a saline infusion site, it may becomecontaminated with saline, leading toabnormal laboratory results. Saline contains a high concentration of sodium chloride, which artificially elevates sodium while diluting other blood components.

Therefore, such samples would display:

Very high sodium levels, and

Abnormally low levelsof other analytes (e.g., proteins, glucose, potassium).

This abnormal pattern (option B) is a classic indicator ofsaline contamination.

Per theGCDMP (Chapter: Data Validation and Cleaning),cross-variable consistency checksare critical for identifying biologically implausible patterns, such as this one, which indicatepre-analytical errorsrather than true physiological changes.

Hence,option Baccurately describes the data signature of a contaminated blood draw.

Reference (CCDM-Verified Sources):

SCDM GCDMP, Chapter: Data Validation and Cleaning, Section 6.2 – Logical and Consistency Checks for Laboratory Data

ICH E6(R2) GCP, Section 5.1.1 – Data Quality and Biological Plausibility Checks

FDA Guidance for Industry: Computerized Systems Used in Clinical Investigations, Section 6.3 – Detecting Laboratory Anomalies