• DEA Form 41 (“Registrants Inventory of Drugs Surrendered”) is the federal form used to document the destruction (disposal) of controlled substances by a registrant.
• Opioid analgesics are controlled substances and therefore require DEA Form 41 for authorized destruction.
• NSAIDs, penicillins, and most monoclonal antibodies are not controlled substances and do not require DEA Form 41 for disposal.
• DEA requirements for controlled substance destruction and recordkeeping (21 CFR; DEA Form 41).
• PTCB/ExCPT law and regulations content outline—forms: 222 (ordering), 106 (theft/loss), 41 (destruction).
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