NABP North American Pharmacist Licensure Examination NAPLEX Question # 13 Topic 2 Discussion
NAPLEX Exam Topic 2 Question 13 Discussion:
Question #: 13
Topic #: 2
Results from a Meta-analysis where they looked at frequency of postoperative arterial fibrillation in patients on Ascorbic acid after cardiac surgery found odds ratio, 0.44 (95% CI, 0.32 to 0.61). How can you interpret this data?
A.
Ascorbic acid increased frequency of postoperative arterial fibrillation after cardiac surgery by 44%
B.
Ascorbic acid decreased frequency of postoperative arterial fibrillation after cardiac surgery by 44%
C.
There was no statistically significant difference in frequency of postoperative arterial fibrillation after cardiac surgery
D.
Ascorbic acid decreased frequency of postoperative arterial fibrillation after cardiac surgery by 56%
Odds ratio of 0.44 (44%) means that this group was associated with an event happening 44% of the time, compared to 1 (an event happening 100% of the time if unexposed), therefore 100 - 44 = 56%, which is the reduction caused by the exposure. Exposure is the use of ascorbic acid.
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