The primary and most critical protocol for the safe storage of hazardous materials is ensuring that chemicals are stored based on theircompatibility, which is determined by referring to theSafety Data Sheets (SDS). Storing incompatible chemicals together—such as oxidizers next to flammables, or acids next to cyanides—can result in catastrophic fires, explosions, or the release of toxic gases if a leak or spill occurs.OSHA 29 CFR 1910.1200(Hazard Communication) mandates that an SDS be available for every chemical, and Section 7 of the SDS specifically details safe storage requirements and incompatible materials.

While hazard categories (Option B) and local codes (Option C) provide helpful high-level frameworks, they are insufficient on their own. For example, two chemicals might both be "corrosive" but could react violently if mixed (e.g., a strong acid and a strong base). A professionalSegregation Planutilizes the specific data from the SDS to create physical distance or secondary containment barriers between reactive groups. TheInternational Fire Code (IFC)andNFPA 400(Hazardous Materials Code) both support this "compatibility-first" approach as the technical foundation for facility safety.

In theCEDPbody of knowledge, safe storage is a major mitigation task. During a disaster, buildings may shift, shelves may collapse, and containers may break. If a facility has ignored compatibility protocols, a simple earthquake or flood can trigger a massive chemical emergency (a "Natech" event). By following the SDS-driven compatibility protocol, emergency managers ensure that even if the primary containers fail, the resulting mixture of materials will not lead to an unmanageable secondary disaster. This systematic approach to "segregation" is the gold standard for reducing risk in industrial, laboratory, and emergency response staging environments.