To enable LUKS on a USB storage device with an ext4 filesystem format, the administrator needs to perform the following steps:

Unmount the device if it is mounted using umount /dev/sdc (D)

Create a partition table on the device using fdisk /dev/sdc (E)

Format the partition with LUKS encryption using cryptsetup luksFormat /dev/sdc1 (H)

Open the encrypted partition using cryptsetup luksOpen /dev/sdc1 LUKS0001

Create an ext4 filesystem on the encrypted partition using mkfs.ext4 /dev/mapper/LUKS0001 ©

Mount the encrypted partition using mount /dev/mapper/LUKS0001 /mnt References:

[CompTIA Linux+ Study Guide], Chapter 9: Securing Linux, Section: Encrypting Disks

[How to Encrypt USB Drive on Ubuntu 18.04]