The CBIC Certified Infection Control Exam Study Guide (6th edition) states that cytomegalovirus (CMV) is a common virus transmitted through direct contact with body fluids, including saliva, urine, blood, and respiratory secretions. In healthcare settings, Standard Precautions are sufficient to prevent CMV transmission, even for pregnant healthcare personnel.

Importantly, routine reassignment, work restriction, or removal from patient care is not recommended for pregnant HCP caring for patients with CMV, including those in the first trimester. The Study Guide emphasizes that the most effective preventive measure is strict adherence to Standard Precautions, particularly hand hygiene and appropriate use of personal protective equipment when contact with body fluids is anticipated. These measures have been shown to significantly reduce the risk of CMV acquisition.

Option A is incorrect because there is no indication for immediate post-exposure evaluation in the absence of a recognized exposure such as a needlestick or mucous membrane contact. Option B is not supported by evidence or guidelines and may contribute to unnecessary workforce restrictions. Option D is insufficient and misleading, as CMV is not transmitted via the airborne route and masking alone does not address the primary transmission risks.

For CIC® exam preparation, it is critical to recognize that education and reinforcement of Standard Precautions—not work exclusion—are the cornerstone of CMV prevention for pregnant healthcare workers.