Medical terms here are very literal.Peri-meansaround,cardirefers to theheart, and-itismeansinflammation. Sopericarditisis inflammation of thepericardium, thefibrous sac surrounding the heart. “With effusion” indicatesfluid accumulationin that pericardial space (pericardial effusion), which can be clinically important because significant effusion may impair heart filling (tamponade risk), but the question is strictly asking which structure is inflamed. Distractors map to other “card-” terms:myocardium(heart muscle) would be “myocarditis,”endocardium(inner lining of chambers/valves) would be “endocarditis,” and blood vessels supplying the heart arecoronary arteries(inflammation would not be termed pericarditis). On CPC exams, identifyingprefix + root + suffixis the fastest method: peri (around) + cardi (heart) + itis (inflammation) → pericardium inflamed.