AACN CCRN (Adult) - Direct Care Eligibility Pathway CCRN-Adult Question # 38 Topic 4 Discussion
CCRN-Adult Exam Topic 4 Question 38 Discussion:
Question #: 38
Topic #: 4
An unconscious patient in hepatic failure secondary to alcoholism becomes acutely hypoglycemic. Glucagon administration is contraindicated for this patient because glucagon
Glucagon is a hormone that stimulates the liver to release glucose from glycogen stores or from gluconeogenesis. However, when the hepatocytes are damaged by alcoholism or other causes of hepatic failure, glucagon is ineffective because the liver cannot respond to its signal. Glucagon administration is contraindicated for hypoglycemic patients with hepatic failure because it will not raise their blood glucose levels and may worsen their acidosis and electrolyte imbalance123
References:
Hypoglycemia in Patients With Hepatic Failure - PubMed
Glucagon - Wikipedia
Frontiers | Glucagon Receptor Signaling and Lipid Metabolism
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